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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
14 DPC

20 matching records from 20 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Shh  sonic hedgehog   (Synonyms: Hhg1)
Results  Reference
1J:171275 Cho SW, Kwak S, Woolley TE, Lee MJ, Kim EJ, Baker RE, Kim HJ, Shin JS, Tickle C, Maini PK, Jung HS, Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth. Development. 2011 May;138(9):1807-16
1J:195713 DeSouza KR, Saha M, Carpenter AR, Scott M, McHugh KM, Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development. PLoS One. 2013;8(1):e53675
1J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8
1J:204539 Gandhi D, Molotkov A, Batourina E, Schneider K, Dan H, Reiley M, Laufer E, Metzger D, Liang F, Liao Y, Sun TT, Aronow B, Rosen R, Mauney J, Adam R, Rosselot C, Van Batavia J, McMahon A, McMahon J, Guo JJ, Mendelsohn C, Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Dev Cell. 2013 Sep 16;26(5):469-82
1*J:53317 Hall JM, Hooper JE, Finger TE, Expression of sonic hedgehog, patched, and Gli1 in developing taste papillae of the mouse. J Comp Neurol. 1999 Apr 5;406(2):143-55
1*J:31122 Iseki S, Araga A, Ohuchi H, Nohno T, Yoshioka H, Hayashi F, Noji S, Sonic hedgehog is expressed in epithelial cells during development of whisker, hair, and tooth. Biochem Biophys Res Commun. 1996 Jan 26;218(3):688-93
1J:237943 Jia S, Kwon HE, Lan Y, Zhou J, Liu H, Jiang R, Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Dev Biol. 2016 Dec 01;420(1):110-119
1*J:308915 Jia S, Oliver JD, Turner EC, Renouard M, Bei M, Wright JT, D'Souza RN, Pax9's Interaction With the Ectodysplasin Signaling Pathway During the Patterning of Dentition. Front Physiol. 2020;11:581843
1J:127453 Kettunen P, Spencer-Dene B, Furmanek T, Kvinnsland IH, Dickson C, Thesleff I, Luukko K, Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning. Mech Dev. 2007 Nov-Dec;124(11-12):868-83
1J:86231 Kim JY, Mochizuki T, Akita K, Jung HS, Morphological evidence of the importance of epithelial tissue during mouse tongue development. Exp Cell Res. 2003 Nov 1;290(2):217-26
1*J:326256 Lee JM, Qin C, Chai OH, Lan Y, Jiang R, Kwon HE, MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity. J Dent Res. 2022 Jul;101(7):832-839
1J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552
1J:260265 O'Connell DJ, Ho JW, Mammoto T, Turbe-Doan A, O'Connell JT, Haseley PS, Koo S, Kamiya N, Ingber DE, Park PJ, Maas RL, A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis. Sci Signal. 2012 Jan 10;5(206):ra4
1J:90053 Ohazama A, Hu Y, Schmidt-Ullrich R, Cao Y, Scheidereit C, Karin M, Sharpe PT, A dual role for Ikk alpha in tooth development. Dev Cell. 2004 Feb;6(2):219-27
1*J:145173 Pantalacci S, Prochazka J, Martin A, Rothova M, Lambert A, Bernard L, Charles C, Viriot L, Peterkova R, Laudet V, Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development. BMC Dev Biol. 2008;8:116
1*J:61488 Pennisi D, Gardner J, Chambers D, Hosking B, Peters J, Muscat G, Abbott C, Koopman P, Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice. Nat Genet. 2000 Apr;24(4):434-7
1*J:59068 Pispa J, Jung HS, Jernvall J, Kettunen P, Mustonen T, Tabata MJ, Kere J, Thesleff I, Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF. Dev Biol. 1999 Dec 15;216(2):521-34
1J:335153 Qiu T, Huteckova B, Seppala M, Cobourne MT, Chen Z, Hovorakova M, Buchtova M, Tucker AS, Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling. Development. 2023 Apr 1;150(7):dev201464
1*J:31152 Vaahtokari A, Aberg T, Jernvall J, Keranen S, Thesleff I, The enamel knot as a signaling center in the developing mouse tooth. Mech Dev. 1996 Jan;54(1):39-43
1J:112545 Wang XP, Aberg T, James MJ, Levanon D, Groner Y, Thesleff I, Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. J Dent Res. 2005 Feb;84(2):138-43

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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory